Nitric oxide formation in acutely rejecting cardiac allografts correlates with GTP cyclohydrolase I activity

Inducible nitric oxide synthase (iNOS) is a prominent component of the complex array of mediators in acute graft rejection. While NO production is determined by iNOS expression, BH(4) (tetrahydrobiopterin), a cofactor of iNOS synthesized by GTP cyclohydrolase I, has been considered critical in susta...

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Detalhes bibliográficos
Main Authors: Pieper, Galen M., Nilakantan, Vani, Halligan, Nadine L. N., Khanna, Ashwani K., Hilton, Gail, Vásquez-Vivar, Jeannette
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2005
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1276954/
https://ncbi.nlm.nih.gov/pubmed/16000090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050575
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