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Generation of protein kinase Ck1α mutants which discriminate between canonical and non-canonical substrates

Protein kinase CK1 denotes a family of pleiotropic serine/threonine protein kinases implicated in a variety of cellular functions. Typically, CK1 acts as a ‘phosphate-directed’ kinase whose targeting is primed by a single phosphorylated side chain at position n−3 or n−4 relative to serine/threonine,...

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Main Authors: Bustos, Victor H., Marin, Oriano, Meggio, Flavio, Cesaro, Luca, Allende, Catherine C., Allende, Jorge E., Pinna, Lorenzo A.
格式: Artigo
語言:Inglês
出版: Portland Press Ltd. 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1276941/
https://ncbi.nlm.nih.gov/pubmed/15975091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050717
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