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The selective recruitment of mRNA to the ER and an increase in initiation are important for glucose-stimulated proinsulin synthesis in pancreatic β-cells

Glucose acutely stimulates proinsulin synthesis in pancreatic β-cells through a poorly understood post-transcriptional mechanism. In the present study, we demonstrate in pancreatic β-cells that glucose stimulates the recruitment of ribosome-associated proinsulin mRNA, located in the cytoplasm, to th...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Greenman, Isabel C., Gomez, Edith, Moore, Claire E. J., Herbert, Terence P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Portland Press Ltd. 2005
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1276927/
https://ncbi.nlm.nih.gov/pubmed/15972000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050468
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