Human Stx2-Specific Monoclonal Antibodies Prevent Systemic Complications of Escherichia coli O157:H7 Infection

Hemolytic-uremic syndrome (HUS) is a serious complication predominantly associated with infection by enterohemorrhagic Escherichia coli (EHEC), such as E. coli O157:H7. EHEC can produce Shiga toxin 1 (Stx1) and/or Shiga toxin 2 (Stx2), both of which are exotoxins comprised of active (A) and binding...

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Autori principali: Mukherjee, Jean, Chios, Kerry, Fishwild, Dianne, Hudson, Deborah, O'Donnell, Susan, Rich, Stephen M., Donohue-Rolfe, Arthur, Tzipori, Saul
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
Soggetti:
Microbial Immunity and Vaccines
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC127659/
https://ncbi.nlm.nih.gov/pubmed/11796590
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