Human Stx2-Specific Monoclonal Antibodies Prevent Systemic Complications of Escherichia coli O157:H7 Infection

Hemolytic-uremic syndrome (HUS) is a serious complication predominantly associated with infection by enterohemorrhagic Escherichia coli (EHEC), such as E. coli O157:H7. EHEC can produce Shiga toxin 1 (Stx1) and/or Shiga toxin 2 (Stx2), both of which are exotoxins comprised of active (A) and binding...

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Pubblicato in:	Infect Immun
Autori principali:	Mukherjee, Jean, Chios, Kerry, Fishwild, Dianne, Hudson, Deborah, O'Donnell, Susan, Rich, Stephen M., Donohue-Rolfe, Arthur, Tzipori, Saul
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2002
Soggetti:	Microbial Immunity and Vaccines
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127659/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11796590/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.70.2.612-619.2002
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