Induction of Gamma Interferon and Nitric Oxide by Truncated Pneumolysin That Lacks Pore-Forming Activity

Pneumolysin (PLY), an important virulence factor of Streptococcus pneumoniae, is known to exert various effects on the host immune cells, including cytokine induction, in addition to its known cytolytic activity as a member of the thiol-activated cytolysins. It is of interest to determine whether cy...

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Autores principales: Baba, Hisashi, Kawamura, Ikuo, Kohda, Chikara, Nomura, Takamasa, Ito, Yutaka, Kimoto, Terumi, Watanabe, Isao, Ichiyama, Satoshi, Mitsuyama, Masao
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2002
Materias:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC127632/
https://ncbi.nlm.nih.gov/pubmed/11748170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.1.107-113.2002
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