Reduced Infectivity of a Leishmania donovani Biopterin Transporter Genetic Mutant and Its Use as an Attenuated Strain for Vaccination

Pterins are essential for the growth of Leishmania species, and recent work has led to the isolation of the biopterin transporter BT1. In this study, we inactivated the Leishmania donovani biopterin transporter BT1 by gene disruption mediated by homologous recombination. No transport of biopterin wa...

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書誌詳細

出版年:	Infect Immun
主要な著者:	Papadopoulou, Barbara, Roy, Gaétan, Breton, Marie, Kündig, Christoph, Dumas, Carole, Fillion, Isabelle, Singh, Ajay K., Olivier, Martin, Ouellette, Marc
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology (ASM) 2002
主題:	Fungal and Parasitic Infections
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127620/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11748164/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.1.62-68.2002
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