Llwytho...

Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol γ

Mitochondrial DNA (mtDNA) mutations and deletions are frequently observed in cancer, and contribute to altered energy metabolism, increased reactive oxygen species (ROS), and attenuated apoptotic response to anticancer agents. The mechanisms by which cells maintain mitochondrial genomic integrity an...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Achanta, Geetha, Sasaki, Ryohei, Feng, Li, Carew, Jennifer S, Lu, Weiqin, Pelicano, Helene, Keating, Michael J, Huang, Peng
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2005
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1276176/
https://ncbi.nlm.nih.gov/pubmed/16163384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600819
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