Interference between D30N and L90M in Selection and Development of Protease Inhibitor-Resistant Human Immunodeficiency Virus Type 1

We studied the evolutionary relationships between the two protease inhibitor (PI) resistance mutations, D30N and L90M, of human immunodeficiency virus type 1 (HIV-1). The former is highly specific for nelfinavir resistance, while the latter is associated with resistance to several PIs, including nel...

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Autori principali: Sugiura, Wataru, Matsuda, Zene, Yokomaku, Yoshiyuki, Hertogs, Kurt, Larder, Brendan, Oishi, Tsuyoshi, Okano, Aiko, Shiino, Teiichirou, Tatsumi, Masashi, Matsuda, Masakazu, Abumi, Hanae, Takata, Noboru, Shirahata, Satoshi, Yamada, Kaneo, Yoshikura, Hiroshi, Nagai, Yoshiyuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
Soggetti:
Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC127489/
https://ncbi.nlm.nih.gov/pubmed/11850252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.3.708-715.2002
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