Gag Non-Cleavage Site Mutations Contribute to Full Recovery of Viral Fitness in Protease Inhibitor-Resistant Human Immunodeficiency Virus Type 1

It is well documented that human immunodeficiency virus type 1 (HIV-1) Gag cleavage site mutations (CSMs) emerge in conjunction with various HIV-1 mutations for protease inhibitor (PI) resistance and improve viral replication capacity, which is reduced by acquisition of the resistance. However, CSMs...

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Main Authors: Myint, Lay, Matsuda, Masakazu, Matsuda, Zene, Yokomaku, Yoshiyuki, Chiba, Tomoko, Okano, Aiko, Yamada, Kaneo, Sugiura, Wataru
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2004
נושאים:
Antiviral Agents
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC321554/
https://ncbi.nlm.nih.gov/pubmed/14742193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.2.444-452.2004
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