Characterization of a New Extended-Spectrum β-Lactamase (TEM-87) Isolated in Proteus mirabilis during an Italian Survey

A new natural TEM derivative, named TEM-87, was identified in a Proteus mirabilis isolate from an Italian hospital. Compared to TEM-1, TEM-87 contains the following mutations: E104K, R164C, and M182T. Kinetic analysis of TEM-87 revealed extended-spectrum activity against oxyimino cephalosporins (pre...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Perilli, Mariagrazia, Segatore, Bernardetta, Massis, Maria Rosaria De, Franceschini, Nicola, Bianchi, Ciro, Rossolini, Gian Maria, Amicosante, Gianfranco
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2002
Schlagworte:	Mechanisms of Resistance
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127476/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11850290/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.3.925-928.2002
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