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Phylogenetic and Familial Estimates of Mitochondrial Substitution Rates: Study of Control Region Mutations in Deep-Rooting Pedigrees

We studied mutations in the mtDNA control region (CR) using deep-rooting French-Canadian pedigrees. In 508 maternal transmissions, we observed four substitutions (0.0079 per generation per 673 bp, 95% CI 0.0023–0.186). Combined with other familial studies, our results add up to 18 substitutions in 1...

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Bibliografiske detaljer
Main Authors: Heyer, Evelyne, Zietkiewicz, Ewa, Rochowski, Andrzej, Yotova, Vania, Puymirat, Jack, Labuda, Damian
Format: Artigo
Sprog:Inglês
Udgivet: The American Society of Human Genetics 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1274355/
https://ncbi.nlm.nih.gov/pubmed/11582570
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