Human Y Chromosome Base-Substitution Mutation Rate Measured by Direct Sequencing in a Deep-Rooting Pedigree

Understanding the key process of human mutation is important for many aspects of medical genetics and human evolution. In the past, estimates of mutation rates have generally been inferred from phenotypic observations or comparisons of homologous sequences among closely related species [1–3]. Here,...

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Detalhes bibliográficos
Main Authors: Xue, Yali, Wang, Qiuju, Long, Quan, Ng, Bee Ling, Swerdlow, Harold, Burton, John, Skuce, Carl, Taylor, Ruth, Abdellah, Zahra, Zhao, Yali, MacArthur, Daniel G., Quail, Michael A., Carter, Nigel P., Yang, Huanming, Tyler-Smith, Chris
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2009
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Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748900/
https://ncbi.nlm.nih.gov/pubmed/19716302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2009.07.032
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