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High mitochondrial mutation rates estimated from deep-rooting Costa Rican pedigrees

Estimates of mutation rates for the noncoding hypervariable Region I (HVR-I) of mitochondrial DNA (mtDNA) vary widely, depending on whether they are inferred from phylogenies (assuming that molecular evolution is clock-like) or directly from pedigrees. All pedigree-based studies so far were conducte...

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Detalhes bibliográficos
Main Authors: Madrigal, Lorena, Castrì, Loredana, Melendez-Obando, Mauricio, Villegas-Palma, Ramon, Barrantes, Ramiro, Raventos, Henrieta, Pereira, Reynaldo, Luiselli, Donata, Pettener, Davide, Barbujani, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377850/
https://ncbi.nlm.nih.gov/pubmed/22460349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajpa.22052
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