Potent and Selective Inhibition of Human Cytomegalovirus Replication by 1263W94, a Benzimidazole l-Riboside with a Unique Mode of Action

Benzimidazole nucleosides have been shown to be potent inhibitors of human cytomegalovirus (HCMV) replication in vitro. As part of the exploration of structure-activity relationships within this series, we synthesized the 2-isopropylamino derivative (3322W93) of 1H-β-d-ribofuranoside-2-bromo-5,6-dic...

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הוצא לאור ב:	Antimicrob Agents Chemother
Principais autores:	Biron, Karen K., Harvey, Robert J., Chamberlain, Stanley C., Good, Steven S., Smith III, Albert A., Davis, Michelle G., Talarico, Christine L., Miller, Wayne H., Ferris, Robert, Dornsife, Ronna E., Stanat, Sylvia C., Drach, John C., Townsend, Leroy B., Koszalka, George W.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology (ASM) 2002
נושאים:	Antiviral Agents
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127361/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12121906/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.8.2365-2372.2002
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