Identification of Small-Molecule Inhibitors of Nucleoside Triphosphate Hydrolase in Toxoplasma gondii

Approximately 150,000 small-molecule compounds were tested by a robotic screening assay for their ability to inhibit nucleoside triphosphate hydrolase (NTPase), a novel enzyme of the tachyzoite form of Toxoplasma gondii. Five unrelated species of compounds were found to inhibit the activities of bot...

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Detaylı Bibliyografya
Asıl Yazarlar: Asai, Takashi, Takeuchi, Tsutomu, Diffenderfer, Jeff, Sibley, L. David
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2002
Konular:
Mechanisms of Action: Physiological Effects
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC127337/
https://ncbi.nlm.nih.gov/pubmed/12121910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.8.2393-2399.2002
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