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Function of the Conserved S1 and KH Domains in Polynucleotide Phosphorylase

We have examined the roles of the conserved S1 and KH RNA binding motifs in the widely dispersed prokaryotic exoribonuclease polynucleotide phosphorylase (PNPase). These domains can be released from the enzyme by mild proteolysis or by truncation of the gene. Using purified recombinant enzymes, we h...

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Detalhes bibliográficos
Main Authors: Stickney, Leigh M., Hankins, Janet S., Miao, Xin, Mackie, George A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1272994/
https://ncbi.nlm.nih.gov/pubmed/16237005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.21.7214-7221.2005
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