Antibacterial Activities and Characterization of Novel Inhibitors of LpxC

Lipid A is the hydrophobic anchor of lipopolysaccharide (LPS) and forms the major lipid component of the outer monolayer of the outer membrane of gram-negative bacteria. Lipid A is required for bacterial growth and virulence, and inhibition of its biosynthesis is lethal to bacteria. UDP-3-O-(R-3-hyd...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Clements, John M., Coignard, Fanny, Johnson, Ian, Chandler, Stephen, Palan, Shilpa, Waller, Andrew, Wijkmans, Jac, Hunter, Michael G.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2002
Sujets:
Mechanisms of Action: Physiological Effects
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC127247/
https://ncbi.nlm.nih.gov/pubmed/12019092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.6.1793-1799.2002
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires