Bactericidal Activity of Increasing Daily and Weekly Doses of Moxifloxacin in Murine Tuberculosis

Moxifloxacin (MXF) is a new 8-methoxyquinolone with potent activity against Mycobacterium tuberculosis and a half-life of 9 to 12 h in humans. Previous in vivo studies using daily doses of 100 mg/kg of body weight have demonstrated bactericidal activity comparable to that of isoniazid (INH) in a mur...

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Autores principales: Yoshimatsu, Tetsuyuki, Nuermberger, Eric, Tyagi, Sandeep, Chaisson, Richard, Bishai, William, Grosset, Jacques
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2002
Materias:
Experimental Therapeutics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC127203/
https://ncbi.nlm.nih.gov/pubmed/12019103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.6.1875-1879.2002
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