Bactericidal Activity of Increasing Daily and Weekly Doses of Moxifloxacin in Murine Tuberculosis

Moxifloxacin (MXF) is a new 8-methoxyquinolone with potent activity against Mycobacterium tuberculosis and a half-life of 9 to 12 h in humans. Previous in vivo studies using daily doses of 100 mg/kg of body weight have demonstrated bactericidal activity comparable to that of isoniazid (INH) in a mur...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Yoshimatsu, Tetsuyuki, Nuermberger, Eric, Tyagi, Sandeep, Chaisson, Richard, Bishai, William, Grosset, Jacques
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2002
Schlagworte:	Experimental Therapeutics
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127203/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12019103/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.6.1875-1879.2002
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