Bactericidal Activity of Increasing Daily and Weekly Doses of Moxifloxacin in Murine Tuberculosis

Moxifloxacin (MXF) is a new 8-methoxyquinolone with potent activity against Mycobacterium tuberculosis and a half-life of 9 to 12 h in humans. Previous in vivo studies using daily doses of 100 mg/kg of body weight have demonstrated bactericidal activity comparable to that of isoniazid (INH) in a mur...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yoshimatsu, Tetsuyuki, Nuermberger, Eric, Tyagi, Sandeep, Chaisson, Richard, Bishai, William, Grosset, Jacques
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2002
Pynciau:
Experimental Therapeutics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC127203/
https://ncbi.nlm.nih.gov/pubmed/12019103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.6.1875-1879.2002
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