Effects of Specific Zidovudine Resistance Mutations and Substrate Structure on Nucleotide-Dependent Primer Unblocking by Human Immunodeficiency Virus Type 1 Reverse Transcriptase

Nucleotide-dependent unblocking of chain-terminated DNA by human immunodeficiency virus type 1 reverse transcriptase (RT) is enhanced by the presence of mutations associated with 3′-azido-3′-deoxythymidine (AZT) resistance. The increase in unblocking activity was greater for mutant combinations asso...

詳細記述

書誌詳細

出版年:	Antimicrob Agents Chemother
主要な著者:	Meyer, Peter R., Matsuura, Suzanne E., Tolun, Adviye A., Pfeifer, Ingrid, So, Antero G., Mellors, John W., Scott, Walter A.
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology (ASM) 2002
主題:	Antiviral Agents
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127181/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11959594/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.5.1540-1545.2002
タグ:	タグ追加 タグなし, このレコードへの初めてのタグを付けませんか!