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Handling Marker-Marker Linkage Disequilibrium: Pedigree Analysis with Clustered Markers

Single-nucleotide polymorphisms (SNPs) are rapidly replacing microsatellites as the markers of choice for genetic linkage studies and many other studies of human pedigrees. Here, we describe an efficient approach for modeling linkage disequilibrium (LD) between markers during multipoint analysis of...

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Bibliografske podrobnosti
Main Authors: Abecasis, Gonçalo R. , Wigginton, Janis E. 
Format: Artigo
Jezik:Inglês
Izdano: American Society of Human Genetics 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1271385/
https://ncbi.nlm.nih.gov/pubmed/16252236
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