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Handling Marker-Marker Linkage Disequilibrium: Pedigree Analysis with Clustered Markers

Single-nucleotide polymorphisms (SNPs) are rapidly replacing microsatellites as the markers of choice for genetic linkage studies and many other studies of human pedigrees. Here, we describe an efficient approach for modeling linkage disequilibrium (LD) between markers during multipoint analysis of...

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Autors principals: Abecasis, Gonçalo R. , Wigginton, Janis E. 
Format: Artigo
Idioma:Inglês
Publicat: American Society of Human Genetics 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1271385/
https://ncbi.nlm.nih.gov/pubmed/16252236
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