Shiga-Like Toxin II Derived from Escherichia coli O157:H7 Modifies Renal Handling of Levofloxacin in Rats

The effect of Shiga-like toxin II (SLT-II) (2 μg/animal), which was derived from Escherichia coli O157:H7, on renal handling of levofloxacin (LVX), a model drug for quinolone antimicrobial agents, was investigated in rats 24 h after intravenous injection. In histopathological examination, acute tubu...

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Autori principali: Zhao, Ying Lan, Cen, Xiao Bo, Ito, Masafumi, Yokoyama, Keiko, Takagi, Kenji, Kitaichi, Kiyoyuki, Nadai, Masayuki, Ohta, Michio, Takagi, Kenzo, Hasegawa, Takaaki
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC127131/
https://ncbi.nlm.nih.gov/pubmed/11959591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.5.1522-1528.2002
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