In Vitro Characterization of A-315675, a Highly Potent Inhibitor of A and B Strain Influenza Virus Neuraminidases and Influenza Virus Replication

A-315675 is a novel, pyrrolidine-based compound that was evaluated in this study for its ability to inhibit A and B strain influenza virus neuraminidases in enzyme assays and influenza virus replication in cell culture. A-315675 effectively inhibited influenza A N1, N2, and N9 and B strain neuramini...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Kati, Warren M., Montgomery, Debra, Carrick, Robert, Gubareva, Larisa, Maring, Clarence, McDaniel, Keith, Steffy, Kevin, Molla, Akhteruzzaman, Hayden, Frederick, Kempf, Dale, Kohlbrenner, William
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2002
Schlagworte:	Antiviral Agents
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127111/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11897583/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.4.1014-1021.2002
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!