In Vitro Characterization of A-315675, a Highly Potent Inhibitor of A and B Strain Influenza Virus Neuraminidases and Influenza Virus Replication

A-315675 is a novel, pyrrolidine-based compound that was evaluated in this study for its ability to inhibit A and B strain influenza virus neuraminidases in enzyme assays and influenza virus replication in cell culture. A-315675 effectively inhibited influenza A N1, N2, and N9 and B strain neuramini...

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Main Authors: Kati, Warren M., Montgomery, Debra, Carrick, Robert, Gubareva, Larisa, Maring, Clarence, McDaniel, Keith, Steffy, Kevin, Molla, Akhteruzzaman, Hayden, Frederick, Kempf, Dale, Kohlbrenner, William
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2002
Assuntos:
Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC127111/
https://ncbi.nlm.nih.gov/pubmed/11897583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.4.1014-1021.2002
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