Oxazolidinone Antibiotics Target the P Site on Escherichia coli Ribosomes

The oxazolidinones are a novel class of antimicrobial agents that target protein synthesis in a wide spectrum of gram-positive and anaerobic bacteria. The oxazolidinone PNU-100766 (linezolid) inhibits the binding of fMet-tRNA to 70S ribosomes. Mutations to oxazolidinone resistance in Halobacterium h...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Aoki, Hiroyuki, Ke, Lizhu, Poppe, Susan M., Poel, Toni J., Weaver, Elizabeth A., Gadwood, Robert C., Thomas, Richard C., Shinabarger, Dean L., Ganoza, M. Clelia
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2002
Soggetti:	Mechanisms of Action: Physiological Effects
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127084/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11897593/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.4.1080-1085.2002
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!