Mechanism of action of oxazolidinones: effects of linezolid and eperezolid on translation reactions.

The oxazolidinones are a new class of synthetic antibiotics with good activity against gram-positive pathogenic bacteria. Experiments with a susceptible Escherichia coli strain, UC6782, demonstrated that in vivo protein synthesis was inhibited by both eperezolid (formerly U-100592) and linezolid (fo...

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Detalhes bibliográficos
Main Authors: Shinabarger, D L, Marotti, K R, Murray, R W, Lin, A H, Melchior, E P, Swaney, S M, Dunyak, D S, Demyan, W F, Buysse, J M
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC164082/
https://ncbi.nlm.nih.gov/pubmed/9333037
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