Mechanism of action of oxazolidinones: effects of linezolid and eperezolid on translation reactions.

The oxazolidinones are a new class of synthetic antibiotics with good activity against gram-positive pathogenic bacteria. Experiments with a susceptible Escherichia coli strain, UC6782, demonstrated that in vivo protein synthesis was inhibited by both eperezolid (formerly U-100592) and linezolid (fo...

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izdano v:	Antimicrob Agents Chemother
Principais autores:	Shinabarger, D L, Marotti, K R, Murray, R W, Lin, A H, Melchior, E P, Swaney, S M, Dunyak, D S, Demyan, W F, Buysse, J M
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1997
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164082/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9333037/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.10.2132
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