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Characterization of Mutations in DNA Gyrase and Topoisomerase IV Involved in Quinolone Resistance of Mycoplasma gallisepticum Mutants Obtained In Vitro

Mycoplasma gallisepticum enrofloxacin-resistant mutants were generated by stepwise selection in increasing concentrations of enrofloxacin. Alterations were found in the quinolone resistance-determining regions of the four target genes encoding DNA gyrase and topoisomerase IV from these mutants. This...

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Detalhes bibliográficos
Main Authors: Reinhardt, A. K., Bébéar, C. M., Kobisch, M., Kempf, I., Gautier-Bouchardon, A. V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC127038/
https://ncbi.nlm.nih.gov/pubmed/11796386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.2.590-593.2002
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