Convulsant and Subconvulsant Doses of Norfloxacin in the Presence and Absence of Biphenylacetic Acid Alter Extracellular Hippocampal Glutamate but Not Gamma-Aminobutyric Acid Levels in Conscious Rats

Fluoroquinolones are antibiotics with central excitatory side effects. These adverse effects presumably result from inhibition of γ-aminobutyric acid (GABA) binding to GABA(A) receptors. This GABA antagonistic effect is greatly potentiated by the active metabolite of fenbufen, biphenylacetic acid (B...

Полное описание

Библиографические подробности

Опубликовано в::	Antimicrob Agents Chemother
Главные авторы:	Smolders, I., Gousseau, C., Marchand, S., Couet, W., Ebinger, G., Michotte, Y.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 2002
Предметы:	Pharmacology
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127025/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11796360/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.2.471-477.2002
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!