Protective Efficacy of a Sulfated Sialyl Lipid (NMSO3) against Human Rotavirus-Induced Diarrhea in a Mouse Model

Antiviral activity of sulfated sialyl lipid (NMSO3) against human rotavirus (RV) was examined in vitro and in vivo. NMSO3 inhibited the replication of four major serotypes (G1 to G4) of human rotavirus with a low 50% effective concentration of 1 to 5 μg/ml and 50% cytotoxic concentration of 153 μg/m...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Antimicrob Agents Chemother
Päätekijät:	Takahashi, Kazuo, Ohashi, Kazutaka, Abe, Yurika, Mori, Shuichi, Taniguchi, Koki, Ebina, Takusaburo, Nakagomi, Osamu, Terada, Masaki, Shigeta, Shiro
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	American Society for Microbiology (ASM) 2002
Aiheet:	Antiviral Agents
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127020/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11796352/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.2.420-424.2002
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