Protective Efficacy of a Sulfated Sialyl Lipid (NMSO3) against Human Rotavirus-Induced Diarrhea in a Mouse Model

Antiviral activity of sulfated sialyl lipid (NMSO3) against human rotavirus (RV) was examined in vitro and in vivo. NMSO3 inhibited the replication of four major serotypes (G1 to G4) of human rotavirus with a low 50% effective concentration of 1 to 5 μg/ml and 50% cytotoxic concentration of 153 μg/m...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Takahashi, Kazuo, Ohashi, Kazutaka, Abe, Yurika, Mori, Shuichi, Taniguchi, Koki, Ebina, Takusaburo, Nakagomi, Osamu, Terada, Masaki, Shigeta, Shiro
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Antiviral Agents
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127020/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11796352/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.2.420-424.2002
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!