Protective Efficacy of a Sulfated Sialyl Lipid (NMSO3) against Human Rotavirus-Induced Diarrhea in a Mouse Model

Antiviral activity of sulfated sialyl lipid (NMSO3) against human rotavirus (RV) was examined in vitro and in vivo. NMSO3 inhibited the replication of four major serotypes (G1 to G4) of human rotavirus with a low 50% effective concentration of 1 to 5 μg/ml and 50% cytotoxic concentration of 153 μg/m...

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Publikašuvnnas:	Antimicrob Agents Chemother
Váldodahkkit:	Takahashi, Kazuo, Ohashi, Kazutaka, Abe, Yurika, Mori, Shuichi, Taniguchi, Koki, Ebina, Takusaburo, Nakagomi, Osamu, Terada, Masaki, Shigeta, Shiro
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	American Society for Microbiology (ASM) 2002
Fáttát:	Antiviral Agents
Liŋkkat:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127020/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11796352/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.2.420-424.2002
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