Single-Dose Intraperitoneal Magainins Improve Survival in a Gram-Negative-Pathogen Septic Shock Rat Model

The therapeutic efficacies of three polycationic peptides selected among the class of the magainins (magainin I, magainin II, and magainin II amide), alone and combined with piperacillin, were investigated in a rat model of septic shock. Rats were given an intraperitoneal injection of 2 × 10(10) CFU...

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Podrobná bibliografie

Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Cirioni, Oscar, Giacometti, Andrea, Ghiselli, Roberto, Mocchegiani, Federico, Fineo, Anna, Orlando, Fiorenza, Prete, Maria Simona Del, Rocchi, Marco, Saba, Vittorio, Scalise, Giorgio
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2002
Témata:	Experimental Therapeutics
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127007/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11751118/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.1.101-104.2002
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