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The C-Terminal Tail of the Polycystin-1 Protein Interacts with the Na,K-ATPase α-Subunit

Polycystin-1 (PC-1) is the product of the PKD1 gene, which is mutated in autosomal dominant polycystic kidney disease. We show that the Na,K-ATPase α-subunit interacts in vitro and in vivo with the final 200 amino acids of the polycystin-1 protein, which constitute its cytoplasmic C-terminal tail. F...

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Detalhes bibliográficos
Main Authors: Zatti, Alessandra, Chauvet, Veronique, Rajendran, Vanathy, Kimura, Thoru, Pagel, Phillip, Caplan, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1266409/
https://ncbi.nlm.nih.gov/pubmed/16107561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-03-0200
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