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A Tat subunit vaccine confers protective immunity against the immune-modulating activity of the human immunodeficiency virus type-1 Tat protein in mice

The rational design of new therapies against HIV-1 necessitates an improved understanding of the mechanisms underlying the production of ineffective immune responses to HIV-1 in most infected individuals. This report shows that the CD8(+) T cell responses to gp120 were greatly diminished in mice vac...

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Detalhes bibliográficos
Main Authors: Agwale, S. M., Shata, M. T., Reitz, M. S., Kalyanaraman, V. S., Gallo, R. C., Popovic, M., Hone, D. M.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC126620/
https://ncbi.nlm.nih.gov/pubmed/12096189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.152313899
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