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Smallpox subunit vaccine produced in planta confers protection in mice

We report here the in planta production of the recombinant vaccinia virus B5 antigenic domain (pB5), an attractive component of a subunit vaccine against smallpox. The antigenic domain was expressed by using efficient transient and constitutive plant expression systems and tested by various immuniza...

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Detalhes bibliográficos
Main Authors: Golovkin, Maxim, Spitsin, Sergei, Andrianov, Vyacheslav, Smirnov, Yuriy, Xiao, Yuhong, Pogrebnyak, Natalia, Markley, Karen, Brodzik, Robert, Gleba, Yuri, Isaacs, Stuart N., Koprowski, Hilary
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1871876/
https://ncbi.nlm.nih.gov/pubmed/17428917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701451104
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