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WWOX gene restoration prevents lung cancer growth in vitro and in vivo

The WWOX (WW domain containing oxidoreductase) gene at the common fragile site, FRA16D, is altered in many types of cancer, including lung cancer. We have examined the tumor suppressor function of WWOX in preclinical lung cancer models. The WWOX gene was expressed in lung cancer cell lines through r...

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Detalhes bibliográficos
Main Authors: Fabbri, Muller, Iliopoulos, Dimitrios, Trapasso, Francesco, Aqeilan, Rami I., Cimmino, Amelia, Zanesi, Nicola, Yendamuri, Sai, Han, Shuang-Yin, Amadori, Dino, Huebner, Kay, Croce, Carlo M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1266103/
https://ncbi.nlm.nih.gov/pubmed/16223882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505485102
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