WWOX gene restoration prevents lung cancer growth in vitro and in vivo

The WWOX (WW domain containing oxidoreductase) gene at the common fragile site, FRA16D, is altered in many types of cancer, including lung cancer. We have examined the tumor suppressor function of WWOX in preclinical lung cancer models. The WWOX gene was expressed in lung cancer cell lines through r...

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Main Authors: Fabbri, Muller, Iliopoulos, Dimitrios, Trapasso, Francesco, Aqeilan, Rami I., Cimmino, Amelia, Zanesi, Nicola, Yendamuri, Sai, Han, Shuang-Yin, Amadori, Dino, Huebner, Kay, Croce, Carlo M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2005
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1266103/
https://ncbi.nlm.nih.gov/pubmed/16223882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505485102
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