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WWOX gene restoration prevents lung cancer growth in vitro and in vivo

The WWOX (WW domain containing oxidoreductase) gene at the common fragile site, FRA16D, is altered in many types of cancer, including lung cancer. We have examined the tumor suppressor function of WWOX in preclinical lung cancer models. The WWOX gene was expressed in lung cancer cell lines through r...

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Bibliographic Details
Main Authors: Fabbri, Muller, Iliopoulos, Dimitrios, Trapasso, Francesco, Aqeilan, Rami I., Cimmino, Amelia, Zanesi, Nicola, Yendamuri, Sai, Han, Shuang-Yin, Amadori, Dino, Huebner, Kay, Croce, Carlo M.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2005
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1266103/
https://ncbi.nlm.nih.gov/pubmed/16223882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505485102
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