Clathrin Adaptor AP-2 Is Essential for Early Embryonal Development

The heterotetrameric adaptor protein (AP) complexes AP-1, AP-2, AP-3, and AP-4 play key roles in transport vesicle formation and cargo sorting in post-Golgi trafficking pathways. Studies on cultured mammalian cells have shown that AP-2 mediates rapid endocytosis of a subset of plasma membrane recept...

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Detalhes bibliográficos
Principais autores: Mitsunari, Takashi, Nakatsu, Fubito, Shioda, Noriko, Love, Paul E., Grinberg, Alexander, Bonifacino, Juan S., Ohno, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265839/
https://ncbi.nlm.nih.gov/pubmed/16227583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.21.9318-9323.2005
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