Impaired Immune Responses and Prolonged Allograft Survival in Sly1 Mutant Mice

Adaptive immunity is crucial for protective host defense and the development of immunological disorders. SLY1 was recently identified as an X-chromosomal SH3 protein that is serine phosphorylated (Ser27) upon B-and T-cell receptor engagement. Here, we demonstrate that SLY1 is localized in the cytopl...

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Bibliografiske detaljer
Main Authors: Beer, Sandra, Scheikl, Tanja, Reis, Bernhard, Hüser, Norbert, Pfeffer, Klaus, Holzmann, Bernhard
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265838/
https://ncbi.nlm.nih.gov/pubmed/16227612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.21.9646-9660.2005
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