AMP-Activated Protein Kinase Protects Cardiomyocytes against Hypoxic Injury through Attenuation of Endoplasmic Reticulum Stress

Oxygen deprivation leads to the accumulation of misfolded proteins in the endoplasmic reticulum (ER), causing ER stress. Under conditions of ER stress, inhibition of protein synthesis and up-regulation of ER chaperone expression reduce the misfolded proteins in the ER. AMP-activated protein kinase (...

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Hlavní autoři: Terai, Kazuo, Hiramoto, Yoshimune, Masaki, Mitsuru, Sugiyama, Shoko, Kuroda, Tadashi, Hori, Masatsugu, Kawase, Ichiro, Hirota, Hisao
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265833/
https://ncbi.nlm.nih.gov/pubmed/16227605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.21.9554-9575.2005
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