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PUMA is critical for neonatal cardiomyocyte apoptosis induced by endoplasmic reticulum stress

OBJECTIVE: Puma (p53-upregulated modulator of apoptosis), a proapoptotic BH3-only member of the Bcl-2 protein family, has been implicated in the pathomechanism of several diseases, including cancer, AIDS, and ischemic brain disease. We have recently shown that Puma is required for cardiac cell death...

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Autores principales: Nickson, Philip, Toth, Ambrus, Erhardt, Peter
Formato: Artigo
Lenguaje:Inglês
Publicado: 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1832123/
https://ncbi.nlm.nih.gov/pubmed/17107669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cardiores.2006.10.001
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