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Optimization of the Cell Wall Microenvironment Allows Increased Production of Recombinant Bacillus anthracis Protective Antigen from B. subtilis

The stability of heterologous proteins secreted by gram-positive bacteria is greatly influenced by the microenvironment on the trans side of the cytoplasmic membrane, and secreted heterologous proteins are susceptible to rapid degradation by host cell proteases. In Bacillus subtilis, degradation occ...

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Detaylı Bibliyografya
Asıl Yazarlar: Thwaite, Joanne E., Baillie, Les W. J., Carter, Noel M., Stephenson, Keith, Rees, Mark, Harwood, Colin R., Emmerson, Peter T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2002
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC126578/
https://ncbi.nlm.nih.gov/pubmed/11772631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.68.1.227-234.2002
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