Optimization of the Cell Wall Microenvironment Allows Increased Production of Recombinant Bacillus anthracis Protective Antigen from B. subtilis

The stability of heterologous proteins secreted by gram-positive bacteria is greatly influenced by the microenvironment on the trans side of the cytoplasmic membrane, and secreted heterologous proteins are susceptible to rapid degradation by host cell proteases. In Bacillus subtilis, degradation occ...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Thwaite, Joanne E., Baillie, Les W. J., Carter, Noel M., Stephenson, Keith, Rees, Mark, Harwood, Colin R., Emmerson, Peter T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2002
Pynciau:
Physiology and Biotechnology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC126578/
https://ncbi.nlm.nih.gov/pubmed/11772631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.68.1.227-234.2002
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