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Cbp Deficiency Alters Csk Localization in Lipid Rafts but Does Not Affect T-Cell Development
The ubiquitously expressed transmembrane adaptor Csk-binding protein (Cbp) recruits Csk to lipid rafts, where the latter exerts its negative regulatory effect on the Src family of protein tyrosine kinases. We have inactivated Cbp in the mouse germ line. In contrast to Csk gene inactivation, which le...
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| Hoofdauteurs: | , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Microbiology
2005
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1265734/ https://ncbi.nlm.nih.gov/pubmed/16166631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.19.8486-8495.2005 |
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