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Asymmetrical division of the kinetoplast DNA network of the trypanosome

Trypanosome mitochondrial DNA is a network containing thousands of interlocked minicircles. Silencing of a mitochondrial topoisomerase II by RNA interference (RNAi) causes progressive network shrinking, allowing assessment of the minimal network size compatible with viability. We cloned surviving ce...

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Autores principales: Wang, Zefeng, Drew, Mark E., Morris, James C., Englund, Paul T.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC126281/
https://ncbi.nlm.nih.gov/pubmed/12234939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf482
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