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Asymmetrical division of the kinetoplast DNA network of the trypanosome

Trypanosome mitochondrial DNA is a network containing thousands of interlocked minicircles. Silencing of a mitochondrial topoisomerase II by RNA interference (RNAi) causes progressive network shrinking, allowing assessment of the minimal network size compatible with viability. We cloned surviving ce...

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Bibliographic Details
Published in:EMBO J
Main Authors: Wang, Zefeng, Drew, Mark E., Morris, James C., Englund, Paul T.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2002
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126281/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12234939/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf482
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